细胞名称

人神经母细胞瘤细胞SK-N-DZ

英文名称

SK-N-DZ

形态特性

成神经细胞样

生长特性

贴壁生长

种属

人

组织

大脑

培养体系

DMEM＋10% FBS＋1% P/S 气相：空气，95%；CO2，5%。  温度：37℃

STR

Amelogenin X CSF1PO 12 D3S1358 17 D5S818 12 D7S820 12,13 D8S1179 12,13 D13S317 8,11 D16S539 9,11 D18S51 15,17 D21S11 29,31 FGA 18,22 Penta D 9,14 Penta E 7,10 TH01 6,9 TPOX 8 vWA 16,18

简介

SK-N-DZ are neuroblasts that were isolated from the brain of a 2-year-old, White female patient with neuroblastoma.SK-N-DZ are neuroblasts that were isolated from the brain of a 2-year-old, White female patient with neuroblastoma. Expression of the N-myc gene product was reduced in differentiated SK-N-DZ cells as compared with undifferentiated cells. Expression of the c-src gene product, pp60c-src was enhanced in differentiated SK-N-DZ cells as was tyrosine phosphorylation of cellular proteins. The cells exhibit moderate MDR1 expression. Retinoic acid induces differentiation in this line.

传代方法

建议第一次1:2传代

冻存条件

90 FBS+10% DMSO, 推荐无血清冻存液 (CX001)

用途

仅限于科学研究，不可作为动物或人类疾病的治疗产品使用。

备注

该细胞贴壁松散，收货如有大块脱落或全部脱落的细胞团，为正常现象，请按照收货注意事项处理。